Can CBD treat epilepsy?

It is estimated that there are close to 4 million people in the US diagnosed with epilepsy of which almost 500,000 are children. Epidiolex CBD for epilepsy and seizures has been approved by the FDA.

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Research has shown potential benefits from CBD administered to dementia patients.

Epilepsy is caused by unusual nerve cell activity in the brain. This activity causes seizures of varying degrees of severity. Unfortunately, current seizure medications are only effective for an estimated 44% of those affected with epileptic seizures. 

The effectiveness of CBD to mitigate seizures has been a focal point of multiple research projects in the past decade. The positive results found in CBD research culminated in 2018 with FDA approval of Epidiolex, a CBD-based medication for childhood epilepsy.

Listed below are links to published CBD research trials that have considered CBD (cannabiniol) in reducing seizures. These research efforts have identified the potential benefits of CBD. This information can help you to decide if CBD is an option for you. You will also see organic, pure CBD products recommended.

Research

Cannabidiol (CBD) for Epilepsy Treatment
VeryWellHealth January 2020

It is not completely clear why CBD can reduce some types of seizures. It is known to have a range of biochemical effects on nerve cells in the brain, some of which may have an impact on seizures.

Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome New England Journal of Medicine May 2017

The median frequency of convulsive seizures per month decreased from 12.4 to 5.9 with cannabidiol, as compared with a decrease from 14.9 to 14.1 with placebo 

CBD may alleviate seizures, benefit behaviors in people with neurodevelopmental conditions ScienceDaily September 2019

CBD, which is a major phytocannabinoid constituent of cannabis, has already shown to have anti-epileptic, anti-anxiety, and anti-psychotic effects. And in 2018, the FDA approved CBD for the treatment of seizures associated with two rare forms of epilepsy, but little is known about the potential anti-seizure and behavioral effects of CBD on Angelman symptom.